What Is It? Why Is It Important? How Do We Measure It? Lab Simulation


Why is it important?

A number of different factors that regulate neurogenesis have been identified.

Physicial activity and environmental conditions have been known to affect proliferation and survival of neurons in vertebrates as well as invertebrates. It has been found that crayfish in an "enriched" environment had increased neurogenesis and neuronal survival compared to siblings in an "impoverished" environment.

Hormones have also been found to influence the rate of neurogenesis in vertebrates (e.g. testosterone) and invertebrates (e.g. ecdysone). Serotonin is believed to play a key role in neurogenesis in a variety of organisms. In lobsters, depletion of serotonin dramatically reduced the proliferation and survival of olfactory projection neurons and local interneurons. Most recently, neurogenesis was found to follow a circadian rhythm in the juvenile lobster. Although neurons were born throughout the day, significantly more neurons were born at dusk, the most active time for lobsters.


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Wellesley College Biology Department :: Last modified: July 11, 2005