HIV part2

The Drugs


From Scientific American


Treatments

 NIH listing of drugs

The reverse transcriptase enzyme is very nonselective and recognizes AZT as an Thymidine This drug gets incorporated into the growing DNA chain and as was the case with acylovir elongation comes to a halt and the virus cannot replicate.

3-TC or epivir works in a similar fasion replacing cytidine in the growing DNA chain. There is a synergistic effect with AZT, as the virus is generally unable to mutate in ways that alow it to resist both drugs.

Ritonavir (left) is one of the protease inhibitors. By binding to and blocking the HIV protease this drug prevents the virus from processing the proteins it makes. By keeping the amount of virus low it prevents HIV from developing resistance to the entire cocktail.

side effects

what the heck is a protease inhibitor

Protease and Inhibitor

ribbons
spacefill
inhibitor
hide inhibitor

Natural Resistance

Cell Protein Gives Monkeys Innate Immunity to H.I.V.

scientific american article
There are others who have a susceptibility towards a rapid onset of AIDS following infection

Side effects of cocktails

the future

 

Made in India, the Ideal `Cocktail' for AIDS