NICOTINE

 


Sir Walter Raleigh


History

 

 

 


a pair of famous smokers

 

BBC series Plants of Power part3 industrial power

 

general info


Biochemistry

nicotine mimics the neurotransmitter acetylcholine(ACh), triggering one of the two types of ACh receptors

ACh and Nicotine

Acetyl Choline

Nicotine

 

 


Two types of receptors

nicotine is an agonist to one type of ACh receptor
muscarine is an antagonist to the other type of receptor
atropine is also an antagonist to ACh receptors

Sarin and VX gases kill by inhibiting the enzyme acetyl choline esterase which clears the ACh from the synapse.
VX


dangers of nicotine

nicotine likened to heroin

wrinkles

 


Philip Morris's idea of an antismoking ad

Real antismoking ads