Journals

(Wellesley undergraduate co-authors are underlined and corresponding authors are denoted with *.)

  1. Zhang, H.; Zhou, R.; Jun, M.; Bacay, A.F.; Eyring, K. Webb, A.; Carrico-Moniz, D.* “Identification of the Factors Responsible for the Selective in vitro Cytotoxic Activity of Isoprenylated Coumarin Derivatives under Nutrient-deprived Conditions.” J.Cancer. 2016. 7, 160-166.
  2. Zhang, H.; Kartub, K.; Kwan, A.; Webb, A.; Carrico-Moniz, D.* “Synthesis and Evaluation of (1S)-1,2-Dihydro-1-Naphthalenol Derivatives Against PANC-1 Cells.” Tetrahedron Lett. 2015. 56, 1720-1723.
  3. Jun, M.; Bacay, A.F.; Moyer, J.; Webb, A.; Carrico-Moniz, D.* “Synthesis and biological evaluation of isoprenylated coumarins as potential anti-pancreatic cancer agents.” Bioorg. Med. Chem. Lett. 2014, 24, 4654- 4658.
  4. Devji, T.; Reddy, C.; Woo, C.; Awale, S.; Kadota, S.; Carrico-Moniz, D.* “Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivative.” Bioorg. Med. Chem. Lett. 2011, 21, 5770-5773.
  5. Kwan, A.; Stein, J.; Carrico-Moniz, D.* “A catalytic asymmetric entry to enantioenriched tertiary naphthoquinols via a facile tandem oxidation/ring-opening sequence.” Tetrahedron Lett. 2011, 52, 3426-3428.
  6. Kazi, A.; Carie, A.; Blaskovich, M.A.; Bucher, C.; Thai, V.; Moulder, S.; Peng, H.; Carrico, D.; Pusateri, E.; Pledger, W.J.; Berndt, N.; Hamilton, A.; Sebti, S.M. “Blockade of protein geranylgeranylation inhibits Cdk2- dependent p27Kip1 phosphorylation on Thr187 and accumulates p27Kip1 in the nucleus: implications for breast cancer therapy”, Mol. Cell Biol. 2009, 29, 2254-2263.
  7. Falsetti, S.C.; Wang, D.A.; Peng, H.; Carrico, D.; Cox, A.D.; Der, C.J.; Hamilton, A.D.; Sebti, S.M. "Geranylgeranyltransferase I Inhibitors Target RalB to Inhibit Anchorage-dependent Growth and Induce Apoptosis and RalA to Inhibit Anchorage-independent Growth." Mol. Cell. Biol. 2007, 27, 8003-8014.
  8. Shults, M.D.; Carrico-Moniz, D.; Imperiali, B. "Optimal Sox-based Fluorescence Chemosensor Design for Serine/Threonine Protein Kinases." Anal. Biochem. 2006, 352, 198-207.
  9. Peng, H.; Carrico, D.; Thai, V.; Blaskovich, M.A.; Bucher, C.J.; Pusateri, E.E.; Sebti, S.M.; Hamilton, A.D. "Synthesis and Evaluation of Potent, Highly Selective, 3-Aryl-piperazinone Inhibitors of Protein Geranylgeranyltransferase-I." Org. Biomol. Chem. 2006, 4, 1768-1784.
  10. Ohkanda, J.; Strickland, C.L.; Blaskovich, M.A.; Carrico, D.; Lockman, J.W.; Vogt, A.; Bucher, C.J.; Sun, J.; Qian, Y.; Knowles, D.; Pusateri, E.E.; Sebti, S.M.; Hamilton, A.D. "Structure-based Design of Imidazole-containing Peptidomimetic Inhibitors of Protein Farnesyltransferase." Org. Biomol. Chem. 2006, 4, 482-492.
  11. Carrico, D.; Blaskovich, M.A.; Bucher, C.J.; Sebti, S.M.; Hamilton, A.D. "Design, Synthesis and Evaluation of Potent and Selective Benzoyleneurea-based Inhibitors of Protein Geranylgeranyltransferase-I." Bioorg. Med. Chem. 2005, 13, 677-688.
  12. Carrico, D.; Ohkanda, J.; Kendrick, H.; Yokoyama, K.; Blaskovich, M.A.; Bucher, C.J.; Buckner, F.S.; Van Voorhis, W.C.; Croft, S.L.; Gelb, M.H.; Sebti, S.M.; Hamilton, A.D. "In vitro and in vivo Antimalarial Activity of Peptidomimetic Protein Farnesyltransferase Inhibitors with Improved Membrane Permeability." Bioorg. Med. Chem. 2004, 12, 6517-6526.
  13. Ohkanda, J.; Buckner, F.S.; Lockman, J.W.; Yokoyama, K.; Carrico, D.; Eastman, R.; Luca-Fradley, K.; Davies, W.; Croft, S.L.; Van Voorhis, W.C.; Gelb, M.H.; Sebti, S.M.; Hamilton, A.D. "Design and Synthesis of Peptidomimetic Protein Farnesyltransferase Inhibitors as Anti-Trypanosoma brucei Agents." J. Med. Chem. 2004, 47, 432-445.
  14. Crespo, N.C.; Delarue, F.; Ohkanda, J.; Carrico, D.; Hamilton, A.D.; Sebti, S.M. "The Farnesyltransferase Inhibitor, FTI-2153, Inhibits Bipolar Spindle Formation During Mitosis Independently of Transformation and Ras and p53 Mutation Status." Cell Death and Differentiation 2002, 9, 702-709.
  15. Karimi, S.; Carrico, D.; Anwar, S. "Tandem Ring Expansion / Aldol Cyclization of Bicyclo [5.4.01,7]undecadiones." Tetrahedron Lett. 2002, 43, 33-35.

Invited Editorial

Carrico-Moniz, D. “Wellesley College Celebrates National Chemistry Week” The Nucleus. Vol. LXXXVIII, No. 5, Jan 2010, page 9.

Patents

Carrico-Moniz, D. “Coumarin Derivatives for Cancer Therapy.” U.S. Patent 9,388,155. Issued July 12, 2016.

Carrico-Moniz, D. “Coumarin Derivatives for Cancer Therapy.” U.S. Patent 9,403,791. Issued August 2, 2016.

Imperiali, B.; Lukovic, E.; Carrico-Moniz, D. “Sox Peptide-based Sensor for Detecting Protein Kinase Activity Using Chelation-enhanced Fluorescence.” (U.S. Patent 7,964,729).

Imperiali, B.; Lukovic, E.; Carrico-Moniz, D. “Sox Peptide-based Sensor for Detecting Protein Kinase Activity Using Chelation-enhanced Fluorescence.” (U.S. Patent 8,586,578).

Presentations/Posters with Wellesley College Students

(Undergraduate co-authors are underlined)

  1. Zhang, H.; Zhou, R.; Jun, M.; Bacay, A.; Webb, A.; Carrico-Moniz, D. “Effect of cell culture components on the preferential cytotoxicity of isoprenylated coumarin derivatives.” 249th ACS National Meeting, Denver, CO, March 2015.
  2. Zhang, H.; Kartub, K.; Zhou, R.; Webb, A.; Carrico-Moniz, D. “Investigating pancreatic anticancer activity of spiroxin A derivatives.” 249th ACS National Meeting, Denver, CO, March 2015.
  3. Kartub, K.; Eyring, K.W.; Solomon, J.; Kwan, A.; Carrico-Moniz, D. “Testing the versatility of a catalytic asymmetric method to prepare enantioenriched tertiary naphthoquinols.” 247th ACS National Meeting, Dallas, TX, March 2014.
  4. Zhang, H.; Lee, E.; Spiegelman, N.; Flynn, N.T.; Carrico-Moniz, D. “Synthesis of an ethylene glycol thiolated hydroquinone molecule to prepare surface-functionalized gold nanoparticles.” 247th ACS National Meeting, Dallas, TX, March 2014.
  5. Eyring, K.W.; Jun, M.; Bacay, A.F.; Webb, A.; Carrico-Moniz, D. “Synthesis and evaluation of a series of novel isoprenylated coumarins as potential anti-pancreatic cancer agents.” 247th ACS National Meeting, Dallas, TX, March 2014.
  6. Spiegelman, N.; Zhang, H.; Hulme, O.; Flynn, N. T.; Carrico-Moniz, D. “Synthesis of a polyethyleneglycol thiolated hydroquinone with enhanced water solubility for surface modification of gold nanoparticles.” 245th ACS National Meeting, New Orleans, LA, April 2013.
  7. Jun, M.; Bacay, A. F.; Carrico-Moniz, D. “Design and Synthesis of a Novel Series of Isoprenylated Coumarins as Potential Anti-Pancreatic Cancer Agents.” 245th ACS National Meeting, New Orleans, LA, April 2013.
  8. Bacay, A. F.; Jun, M.; Moyer, J.; Webb, A.; Carrico-Moniz, D. “Biological evaluation of a novel series of isoprenylated coumarins as promising pancreatic cancer therapies.” 245th ACS National Meeting, New Orleans, LA, April 2013.
  9. Hulme, O. L.; Vu, L. H.; Flynn, N. T.; Carrico-Moniz, D. “Progress towards the synthesis of a novel ethyleneglycol-thiolated hydroquinone molecule for surface modification of gold nanoparticles.” 243rd ACS National Meeting, San Diego, CA, March 2012.
  10. Jun, M.; Devji, T.; Webb, A.; Carrico-Moniz, D. “Design, synthesis, and evaluation of a novel series of isoprenylated coumarins as promising pancreatic cancer therapeutics.” 243rd ACS National Meeting, San Diego, CA, March 2012.
  11. Kwan, A. K. Y.; Stein, J.; Carrico-Moniz, D. “Synthesis of a key chiral precursor for the total synthesis of the natural product Spiroxin A.” 241st ACS National Meeting, Anaheim, CA, March 2011.
  12. Devji, T.; Carrico-Moniz, D. “Design, synthesis, and evaluation of novel isoprenyl coumarin derivatives as potential antiviral and anticancer agents.” 241st ACS National Meeting, Anaheim, CA, March 2011.
  13. Vu, L. H.; Hulme, O. L.; Flynn, N. T.; Carrico-Moniz, D. “Synthesis of electroactive molecules for surface modification of gold nanoparticles.” 241st ACS National Meeting, Anaheim, CA, March 2011.
  14. Ngai, K.Y.; Woo, C.; Carrico-Moniz, D. “Progress toward the total (±) angelmarin and structural analogs as potential anticancer agents.” 237th ACS National Meeting, Salt Lake City, UT, March 2009.
  15. Lodhia, N.A.; Carrico-Moniz, D. “Progress toward the synthesis of a novel series of hepatitis C NS3/4A protease inhibitors.” 237th ACS National Meeting, Salt Lake City, UT, March 2009.
  16. Reddy, C.B.; Badea, A.; Carrico-Moniz, D. “Design and synthesis of structural analogs of the natural product angelmarin to target pancreatic cancer.” 237th ACS National Meeting, Salt Lake City, UT, March 2009.
  17. Woo, C.; Ngai, J.; Carrico-Moniz, D. “Synthetic studies towards (+)-Angelmarin: A natural product targeting pancreatic cancer.” 236th ACS National Meeting, Philadelphia, PA, August 2008.
  18. Woo, C.; Ngai, J.; Carrico-Moniz, D. “Progress toward the enantioselective total synthesis of angelmarin: A natural product targeting pancreatic cancer.” 235th ACS National Meeting, New Orleans, LA, April 2008.